PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19664596-5 2009 Since NDI1 can functionally complement the complex I under the presence of metformin or rotenone, our results indicate that metformin induces down-regulation of G6pc expression through an inhibition of complex I and an activation of AMPK-independent mechanism. Rotenone 88-96 NADH-ubiquinone reductase (H(+)-translocating) NDI1 Saccharomyces cerevisiae S288C 6-10