PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19661014-0	2009	Macrolide antibiotics like azithromycin increase lipopolysaccharide-induced IL-8 production by human gingival fibroblasts.	Azithromycin	27-39	C-X-C motif chemokine ligand 8	Homo sapiens	76-80	
19661014-7	2009	AZM increased PgLPS-induced IL-8 production dose-dependently, while AZM did not alter IL-6 and PGE2 productions.	Azithromycin	0-3	C-X-C motif chemokine ligand 8	Homo sapiens	28-32	
19661014-11	2009	However, the use of the inhibitors of cell signaling pathway failed to reveal the mechanism that AZM enhanced PgLPS-induced IL-8 production.	Azithromycin	97-100	C-X-C motif chemokine ligand 8	Homo sapiens	124-128	
19661014-13	2009	Because AZM increased LPS-induced IL-8 production by HGFs, the possibility is considered that neutrophils may be migrated to periodontal tissue and phagocytize the periodontopathic bacteria more efficiently.	Azithromycin	8-11	C-X-C motif chemokine ligand 8	Homo sapiens	34-38