PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19539481-6 2009 As hCA VA/VB are involved in several biosynthetic processes catalyzed by pyruvate carboxylase, acetyl CoA carboxylase, and carbamoyl phosphate synthetases I and II, providing the bicarbonate substrate to these carboxylating enzymes involved in fatty acid biosynthesis, their selective inhibition may lead to the development of antiobesity agents possessing a new mechanism of action. Fatty Acids 244-254 carbonic anhydrase 5A Homo sapiens 3-9