PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19478080-1 2009 In mammals, nicotinamide phosphoribosyltransferase (NAMPT) and nicotinamide mononucleotide adenylyltransferase 1 (NMNAT-1) constitute a nuclear NAD(+) salvage pathway which regulates the functions of NAD(+)-dependent enzymes such as the protein deacetylase SIRT1. NAD 144-150 nicotinamide nucleotide adenylyltransferase 1 Homo sapiens 63-112 19478080-1 2009 In mammals, nicotinamide phosphoribosyltransferase (NAMPT) and nicotinamide mononucleotide adenylyltransferase 1 (NMNAT-1) constitute a nuclear NAD(+) salvage pathway which regulates the functions of NAD(+)-dependent enzymes such as the protein deacetylase SIRT1. NAD 144-150 nicotinamide nucleotide adenylyltransferase 1 Homo sapiens 114-121 19478080-1 2009 In mammals, nicotinamide phosphoribosyltransferase (NAMPT) and nicotinamide mononucleotide adenylyltransferase 1 (NMNAT-1) constitute a nuclear NAD(+) salvage pathway which regulates the functions of NAD(+)-dependent enzymes such as the protein deacetylase SIRT1. NAD 200-206 nicotinamide nucleotide adenylyltransferase 1 Homo sapiens 63-112 19478080-1 2009 In mammals, nicotinamide phosphoribosyltransferase (NAMPT) and nicotinamide mononucleotide adenylyltransferase 1 (NMNAT-1) constitute a nuclear NAD(+) salvage pathway which regulates the functions of NAD(+)-dependent enzymes such as the protein deacetylase SIRT1. NAD 200-206 nicotinamide nucleotide adenylyltransferase 1 Homo sapiens 114-121 19478080-4 2009 In this study we show that stable short hairpin RNA-mediated knockdown of NAMPT or NMNAT-1 in MCF-7 breast cancer cells reduces total cellular NAD(+) levels and alters global patterns of gene expression. NAD 143-149 nicotinamide nucleotide adenylyltransferase 1 Homo sapiens 83-90