PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19435901-3 2009 Here, we have developed an inducible oral-specific animal tumor model system, which consists in the expression of a tamoxifen-inducible Cre recombinase (CreER(tam)) under the control of the cytokeratin 14 (K14) promoter (K14-CreER(tam)) and mice in which the endogenous K-ras locus is targeted (LSL-K-ras(G12D)), thereby causing the expression of endogenous levels of oncogenic K-ras(G12D) following removal of a stop element. Tamoxifen 116-125 keratin 14 Mus musculus 190-204