PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19416642-7	2009	Using immunoblot analysis we found that nM concentrations of PGE(2) strongly stimulated the phosphorylation of ERK 1/2 by the EP(3-II) and EP(3-III) isoforms; whereas, ERK 1/2 phosphorylation by the EP(3-Ia) isoform was minimal and only occurred at muM concentrations of PGE(2).	Prostaglandins E	61-64	prostaglandin E receptor 3	Homo sapiens	126-133	
19416642-7	2009	Using immunoblot analysis we found that nM concentrations of PGE(2) strongly stimulated the phosphorylation of ERK 1/2 by the EP(3-II) and EP(3-III) isoforms; whereas, ERK 1/2 phosphorylation by the EP(3-Ia) isoform was minimal and only occurred at muM concentrations of PGE(2).	Prostaglandins E	61-64	prostaglandin E receptor 3	Homo sapiens	139-147	
19416642-8	2009	Furthermore, the mechanisms of the PGE(2) mediated phosphorylation of ERK 1/2 by the EP(3-II) and EP(3-III) isoforms were different.	Prostaglandins E	35-38	prostaglandin E receptor 3	Homo sapiens	85-92	
19416642-8	2009	Furthermore, the mechanisms of the PGE(2) mediated phosphorylation of ERK 1/2 by the EP(3-II) and EP(3-III) isoforms were different.	Prostaglandins E	35-38	prostaglandin E receptor 3	Homo sapiens	98-106	
19416642-9	2009	Thus, PGE(2) stimulation of ERK 1/2 phosphorylation by the EP(3-III) isoform involves activation of a Galpha(i)/PI3K/PKC/Src and EGFR-dependent pathway; while for the EP(3-II) isoform it involves activation of a Galpha(i)/Src and EGFR-dependent pathway.	Prostaglandins E	6-9	prostaglandin E receptor 3	Homo sapiens	59-67	
19416642-9	2009	Thus, PGE(2) stimulation of ERK 1/2 phosphorylation by the EP(3-III) isoform involves activation of a Galpha(i)/PI3K/PKC/Src and EGFR-dependent pathway; while for the EP(3-II) isoform it involves activation of a Galpha(i)/Src and EGFR-dependent pathway.	Prostaglandins E	6-9	prostaglandin E receptor 3	Homo sapiens	59-66