PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19403828-2	2009	In vivo, estradiol can inhibit or stimulate GnRH release depending on concentration and physiological state.	Estradiol	9-18	gonadotropin releasing hormone 1	Mus musculus	44-48	
19403828-12	2009	Without blockade of ionotropic GABA and glutamate receptors, however, 10 pm estradiol reduced firing of GnRH neurons; this was mimicked by an ERalpha agonist.	Estradiol	76-85	gonadotropin releasing hormone 1	Mus musculus	104-108	
19403828-15	2009	These data suggest rapid intrinsic and network modulation of GnRH neurons by estradiol is dependent on both dose and receptor subtype.	Estradiol	77-86	gonadotropin releasing hormone 1	Mus musculus	61-65