PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19361439-0	2009	Differential responses of the backbone and side-chain conformational dynamics in FKBP12 upon binding the transition-state analog FK506: implications for transition-state stabilization and target protein recognition.	Tacrolimus	129-134	FKBP prolyl isomerase 1A pseudogene 4	Homo sapiens	81-87	
19361439-2	2009	The macrolide FK506 is a transition-state analog of the catalyzed reaction and displaces FKBP12 from its natural target proteins.	Tacrolimus	14-19	FKBP prolyl isomerase 1A pseudogene 4	Homo sapiens	89-95	
19361439-3	2009	We compared the conformational exchange dynamics of the backbone and methyl-bearing side chains of FKBP12 in the free and FK506-bound states using NMR relaxation-dispersion experiments.	Tacrolimus	122-127	FKBP prolyl isomerase 1A pseudogene 4	Homo sapiens	99-105	
19361439-5	2009	In FK506-bound FKBP12, the backbone is confined to a single conformation, while conformational exchange prevails for many methyl groups.	Tacrolimus	3-8	FKBP prolyl isomerase 1A pseudogene 4	Homo sapiens	15-21