PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19345729-4 2009 The effects of mitochondrial superoxide scavenger on glucose-induced alterations in MMP-2, and its proenzyme activator MT1-MMP and physiological inhibitor TIMP-2, were determined in retinal endothelial cells, and the regulation of their glucose-induced accelerated apoptosis by the inhibitors of MMP-2 was accessed. Superoxides 29-39 matrix metallopeptidase 2 Rattus norvegicus 84-89 19345729-6 2009 Glucose-induced activation of retinal capillary cell MMP-2 and MT1-MMP and decrease in TIMP-2 were inhibited by superoxide scavengers, and their accelerated apoptosis was prevented by the inhibitors of MMP-2. Superoxides 112-122 matrix metallopeptidase 2 Rattus norvegicus 53-58 19345729-6 2009 Glucose-induced activation of retinal capillary cell MMP-2 and MT1-MMP and decrease in TIMP-2 were inhibited by superoxide scavengers, and their accelerated apoptosis was prevented by the inhibitors of MMP-2. Superoxides 112-122 matrix metallopeptidase 2 Rattus norvegicus 202-207 19345729-8 2009 Thus, MMP-2 has a proapoptotic role in the loss of retinal capillary cells in diabetes, and the activation of MMP-2 is under the control of superoxide. Superoxides 140-150 matrix metallopeptidase 2 Rattus norvegicus 110-115