PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19299583-0	2009	Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis.	NAD	54-58	clock circadian regulator	Homo sapiens	10-15	
19299583-2	2009	Here we report that both the rate-limiting enzyme in mammalian nicotinamide adenine dinucleotide (NAD+) biosynthesis, nicotinamide phosphoribosyltransferase (NAMPT), and levels of NAD+ display circadian oscillations that are regulated by the core clock machinery in mice.	NAD	63-96	clock circadian regulator	Homo sapiens	247-252	
19299583-2	2009	Here we report that both the rate-limiting enzyme in mammalian nicotinamide adenine dinucleotide (NAD+) biosynthesis, nicotinamide phosphoribosyltransferase (NAMPT), and levels of NAD+ display circadian oscillations that are regulated by the core clock machinery in mice.	NAD	98-102	clock circadian regulator	Homo sapiens	247-252	
19299583-4	2009	In turn, the circadian transcription factor CLOCK binds to and up-regulates Nampt, thus completing a feedback loop involving NAMPT/NAD+ and SIRT1/CLOCK:BMAL1.	NAD	131-135	clock circadian regulator	Homo sapiens	44-49