PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19286663-5 2009 In view of recent observations, we hypothesized that the SOD1 peroxidase cycle relies on two steps: 1) reduction of SOD-Cu(II) by hydrogen peroxide followed by 2) oxidation of SOD-Cu(I) by peroxymonocarbonate, the product of the spontaneous reaction of bicarbonate with hydrogen peroxide, to produce SOD-Cu(II) and carbonate radical anion. Bicarbonates 253-264 superoxide dismutase 1 Homo sapiens 57-61