PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19277216-8 2009 The shift of E(GABA) from the depolarizing to the hyperpolarizing direction with bumetanide, a blocker of the cation-chloride co-transporter NKCC1, prevented synaptic potentiation and caused synaptic depression, suggesting that the depolarizing action of GABA observed in the presence of CGP55845 is responsible for the potentiating effect. CGP 55845A 288-296 solute carrier family 12 member 2 Homo sapiens 141-146