PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19171939-10	2009	We propose that the functional specialization of Sir3, itself a paralog of Orc1, as a silencing protein was facilitated by the tandem duplication of the OIR domain in the Sir1 family, allowing distinct Sir1-Sir3 and Sir1-Orc1 interactions through OIR-BAH domain interactions.	bis(5-amidino-2-benzimidazolyl)methane ketone hydrate	251-254	chromatin-silencing protein SIR3	Saccharomyces cerevisiae S288C	49-53