PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19116140-6 2009 Our results also indicate that signaling events downstream of EGF receptor involved PI3K- and Src-dependent activation of Rac1, which mediated the NADPH-generated reactive oxygen species responsible for MMP-2 secretion and activation. Reactive Oxygen Species 163-186 epidermal growth factor receptor Homo sapiens 62-74