PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1911530-0	1991	Production of citrulline and ornithine by interferon-gamma treated macrophages.	Ornithine	29-38	interferon gamma	Mus musculus	42-58	
1911530-3	1991	In view of the physiological importance of ornithine and putrescine, we now investigated whether interferon-gamma (IFN-gamma), a principal stimulator of the OAD activity, may lead to the accumulation of the deiminated derivative citrulline at the expense of ornithine production, or whether the carbon backbone could be reutilized for the production of arginine and ornithine.	Ornithine	258-267	interferon gamma	Mus musculus	97-113	
1911530-3	1991	In view of the physiological importance of ornithine and putrescine, we now investigated whether interferon-gamma (IFN-gamma), a principal stimulator of the OAD activity, may lead to the accumulation of the deiminated derivative citrulline at the expense of ornithine production, or whether the carbon backbone could be reutilized for the production of arginine and ornithine.	Ornithine	258-267	interferon gamma	Mus musculus	115-124	
1911530-3	1991	In view of the physiological importance of ornithine and putrescine, we now investigated whether interferon-gamma (IFN-gamma), a principal stimulator of the OAD activity, may lead to the accumulation of the deiminated derivative citrulline at the expense of ornithine production, or whether the carbon backbone could be reutilized for the production of arginine and ornithine.	Ornithine	258-267	interferon gamma	Mus musculus	97-113	
1911530-3	1991	In view of the physiological importance of ornithine and putrescine, we now investigated whether interferon-gamma (IFN-gamma), a principal stimulator of the OAD activity, may lead to the accumulation of the deiminated derivative citrulline at the expense of ornithine production, or whether the carbon backbone could be reutilized for the production of arginine and ornithine.	Ornithine	258-267	interferon gamma	Mus musculus	115-124	
1911530-8	1991	However, when TNF or LPS stimulated macrophages are simultaneously treated with IFN-gamma, ornithine production is relatively inhibited by the strong OAD reaction that competes with the ASE reaction for its substrate L-arginine.	Ornithine	91-100	interferon gamma	Mus musculus	80-89	
1911530-9	1991	IFN-gamma thus down-regulates the availability of ornithine and putrescine.	Ornithine	50-59	interferon gamma	Mus musculus	0-9