PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19023330-4 2009 We also show that loss of HtrA2 results in the accumulation of unfolded proteins in the mitochondria, defective mitochondrial respiration and enhanced production of reactive oxygen species that contribute to the induction of CHOP expression and to neuronal cell death. Oxygen 174-180 DNA damage inducible transcript 3 Homo sapiens 225-229