PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18989785-0	2008	Involvement of endoplasmic reticulum stress in Docetaxel-induced JNK-dependent apoptosis of human melanoma.	Docetaxel	47-56	mitogen-activated protein kinase 8	Homo sapiens	65-68	
18989785-1	2008	Our previous studies revealed that Docetaxel-induced apoptosis of melanoma cells is entirely dependent on activation of the JNK signalling pathway.	Docetaxel	35-44	mitogen-activated protein kinase 8	Homo sapiens	124-127	
18989785-4	2008	Knockdown of IRE1alpha by siRNA markedly inhibited Docetaxel-induced JNK activation and downstream targets of JNK indicating that activation of IRE1alpha was upstream of activation of the JNK.	Docetaxel	51-60	mitogen-activated protein kinase 8	Homo sapiens	69-72	
18989785-4	2008	Knockdown of IRE1alpha by siRNA markedly inhibited Docetaxel-induced JNK activation and downstream targets of JNK indicating that activation of IRE1alpha was upstream of activation of the JNK.	Docetaxel	51-60	mitogen-activated protein kinase 8	Homo sapiens	110-113	
18989785-4	2008	Knockdown of IRE1alpha by siRNA markedly inhibited Docetaxel-induced JNK activation and downstream targets of JNK indicating that activation of IRE1alpha was upstream of activation of the JNK.	Docetaxel	51-60	mitogen-activated protein kinase 8	Homo sapiens	110-113	
18989785-6	2008	ER stress mediated activation of the JNK pathway is downstream of activation of PKCdelta in that downregulation of PKCdelta expression using specific PKCdelta siRNA significantly inhibited Docetaxel-induced activation of IRE1alpha and the JNK pathway.	Docetaxel	189-198	mitogen-activated protein kinase 8	Homo sapiens	37-40	
18989785-6	2008	ER stress mediated activation of the JNK pathway is downstream of activation of PKCdelta in that downregulation of PKCdelta expression using specific PKCdelta siRNA significantly inhibited Docetaxel-induced activation of IRE1alpha and the JNK pathway.	Docetaxel	189-198	mitogen-activated protein kinase 8	Homo sapiens	239-242