PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1896431-5 1991 The significance of some changes in the catalytic site is uncertain due to the intrusion of a symmetry related Lys-70 side chain which hydrogen bonds to both Asp-21 and Glu-43. Hydrogen 135-143 beta-secretase 2 Homo sapiens 158-164