PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18957427-8	2008	Moreover, the expression of dominant-negative Rab5, unable to exchange GDP for GTP, interfered with the agonist-induced dissociation of Rab5 from the syndecan-1 cytoplasmic domain and significantly inhibited syndecan-1 shedding induced by several distinct agonists.	Guanosine Diphosphate	71-74	RAB5A, member RAS oncogene family	Homo sapiens	46-50	
18957427-9	2008	Based on these data, we propose that Rab5 is a critical regulator of syndecan-1 shedding that serves as an on-off molecular switch through its alternation between the GDP-bound and GTP-bound forms.	Guanosine Diphosphate	167-170	RAB5A, member RAS oncogene family	Homo sapiens	37-41