PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18815253-0	2008	Region-specific changes in the subcellular distribution of AMPA receptor GluR1 subunit in the rat ventral tegmental area after acute or chronic morphine administration.	Morphine	144-152	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	73-78	
18815253-3	2008	Indeed, chronic morphine administration is known to increase AMPA receptor glutamate receptor 1 (GluR1) subunit in the VTA.	Morphine	16-24	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	75-95	
18815253-3	2008	Indeed, chronic morphine administration is known to increase AMPA receptor glutamate receptor 1 (GluR1) subunit in the VTA.	Morphine	16-24	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	97-102	
18815253-6	2008	Acute morphine administration produced a significant increase in GluR1 immunogold particles at the plasma membrane and postsynaptic densities in both TH- and non-TH-containing dendrites in the parabrachial VTA, a region that contains mainly prefrontal-cortical-projecting dopaminergic neurons involved in motivation and drug-seeking behavior.	Morphine	6-14	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	65-70	
18815253-7	2008	Chronic morphine administration maintained the increased synaptic GluR1 labeling in the parabrachial VTA, but also increased the number of GluR1-labeled synapses and TH immunoreactivity in dendrites of the paranigral VTA where substantially more dopaminergic neurons project to limbic structures implicated in locomotor activation and reward.	Morphine	8-16	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	66-71	
18815253-7	2008	Chronic morphine administration maintained the increased synaptic GluR1 labeling in the parabrachial VTA, but also increased the number of GluR1-labeled synapses and TH immunoreactivity in dendrites of the paranigral VTA where substantially more dopaminergic neurons project to limbic structures implicated in locomotor activation and reward.	Morphine	8-16	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	139-144	
18815253-8	2008	These results demonstrate a region- and dose-dependent redistribution of GluR1-containing AMPA receptors, which is consistent with acute morphine activation of cortical-projecting VTA neurons and chronic morphine activation of limbic-projecting VTA neurons.	Morphine	137-145	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	73-78	
18815253-8	2008	These results demonstrate a region- and dose-dependent redistribution of GluR1-containing AMPA receptors, which is consistent with acute morphine activation of cortical-projecting VTA neurons and chronic morphine activation of limbic-projecting VTA neurons.	Morphine	204-212	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	73-78