PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18725521-4 2008 In this study, we show that polyinosinic:polycytidylic acid (poly[I:C]) and lipopolysaccharide stimulation of macrophages induces pro-IL-1beta processing via a Toll/IL-1R domain-containing adaptor-inducing interferon-beta-dependent signaling pathway that is initiated by TLR3 and TLR4, respectively. Poly C 41-59 toll like receptor 4 Homo sapiens 160-164 18725521-4 2008 In this study, we show that polyinosinic:polycytidylic acid (poly[I:C]) and lipopolysaccharide stimulation of macrophages induces pro-IL-1beta processing via a Toll/IL-1R domain-containing adaptor-inducing interferon-beta-dependent signaling pathway that is initiated by TLR3 and TLR4, respectively. Poly C 41-59 toll like receptor 4 Homo sapiens 280-284