PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18547621-10 2008 BRCA mutation analysis identified germline BRCA1 mutation for further testing and this xenograft showed a significant response to carboplatin/paclitaxel chemotherapy, including a decrease in tumor volume and proliferation but did not demonstrate a response to the poly (ADP-ribose) polymerase-1 inhibitor PJ34. Paclitaxel 142-152 BRCA1 DNA repair associated Homo sapiens 0-4