PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18466776-0 2008 MsrA knockout mouse exhibits abnormal behavior and brain dopamine levels. Dopamine 57-65 methionine sulfoxide reductase A Mus musculus 0-4 18466776-8 2008 Surprisingly, relative to wild-type mice, MsrA(-/-) brains contained significantly higher levels of dopamine up to 12 months of age, while lower levels of dopamine were observed at 16 months of age. Dopamine 100-108 methionine sulfoxide reductase A Mus musculus 42-46 18466776-9 2008 Moreover, striatal regions of MsrA(-/-) mice showed an increase of dopamine release parallel to observed dopamine levels. Dopamine 67-75 methionine sulfoxide reductase A Mus musculus 30-34 18466776-9 2008 Moreover, striatal regions of MsrA(-/-) mice showed an increase of dopamine release parallel to observed dopamine levels. Dopamine 105-113 methionine sulfoxide reductase A Mus musculus 30-34 18466776-11 2008 Thus, it is suggested that dopamine regulation and signaling pathways are impaired in MsrA(-/-) mice, which may contribute to their abnormal behavior. Dopamine 27-35 methionine sulfoxide reductase A Mus musculus 86-90