PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18455202-3 2008 In this study we describe the establishment of a Bioluminescence Resonance Energy Transfer (BRET) assay for measuring dopamine induced recruitment of human beta-arrestin2 to the human dopamine D2 receptor. Dopamine 118-126 arrestin beta 2 Homo sapiens 156-170 18455202-4 2008 Dopamine, as well as the dopamine receptor agonists pramipexole and quinpirole, acted as full agonists in the assay as reflected by their ability to elicit marked concentration dependent increases in the BRET signal signifying beta-arrestin2 recruitment to the D2 receptor. Dopamine 0-8 arrestin beta 2 Homo sapiens 227-241 18455202-7 2008 Moreover, we observed that haloperidol, sertindole, olanzapine, clozapine and ziprasidone all fully inhibited the dopamine induced beta-arrestin2 recruitment to D2 receptor (short variant) in a concentration dependent manner. Dopamine 114-122 arrestin beta 2 Homo sapiens 131-145