PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18434534-0	2008	Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine.	Memantine	99-108	caspase 3	Homo sapiens	19-28	
18434534-8	2008	Memantine (4 microM) inhibited isoflurane-induced elevations in cytosolic calcium levels and attenuated isoflurane-induced caspase-3 activation, apoptosis, and cell viability.	Memantine	0-9	caspase 3	Homo sapiens	123-132	
18434534-12	2008	We also show for the first time that the NMDA receptor partial antagonist, memantine, can prevent isoflurane-induced caspase-3 activation and apoptosis in vivo and in vitro.	Memantine	75-84	caspase 3	Homo sapiens	117-126