PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18403484-5 2008 Using Western blot analysis, we found that dexamethasone rapidly activates ERK, c-jun N-terminal kinase (JNK), and p38 MAPK in human umbilical vein endothelial cells. Dexamethasone 43-56 mitogen-activated protein kinase 8 Homo sapiens 80-103 18403484-5 2008 Using Western blot analysis, we found that dexamethasone rapidly activates ERK, c-jun N-terminal kinase (JNK), and p38 MAPK in human umbilical vein endothelial cells. Dexamethasone 43-56 mitogen-activated protein kinase 8 Homo sapiens 105-108 18403484-7 2008 Using EMSA and a decoy oligonucleotide approach, the transcription factors activator protein-1 (activated by ERK and JNK) and cAMP response element-binding protein (activated by ERK) were found to be involved in the up-regulation of MKP-1 by dexamethasone. Dexamethasone 242-255 mitogen-activated protein kinase 8 Homo sapiens 117-120 18403484-8 2008 Interestingly, dexamethasone induces the generation of reactive oxygen species (measured by dihydrofluorescein assay), which participate in the signaling process by triggering JNK activation. Dexamethasone 15-28 mitogen-activated protein kinase 8 Homo sapiens 176-179