PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18374906-0	2008	Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice.	Ibuprofen	0-9	histocompatibility 2, class II antigen A, beta 1	Mus musculus	18-23	
18374906-5	2008	Ibuprofen-treated transgenic mice showed a significant decrease in intraneuronal oligomeric Abeta and hyperphosphorylated tau (AT8) immunoreactivity in the hippocampus.	Ibuprofen	0-9	histocompatibility 2, class II antigen A, beta 1	Mus musculus	92-97	
18374906-6	2008	Confocal microscopy demonstrated co-localization of conformationally altered (MC1) and early phosphorylated tau (CP-13) with oligomeric Abeta, and less co-localization of oligomeric Abeta and later forms of phosphorylated tau (AT8 and PHF-1) in untreated 3xTg-AD mice.	cp-13	113-118	histocompatibility 2, class II antigen A, beta 1	Mus musculus	136-141	
18374906-7	2008	Our findings show that prophylactic treatment of young 3xTg-AD mice with ibuprofen reduces intraneuronal oligomeric Abeta, reduces cognitive deficits, and prevents hyperphosphorylated tau immunoreactivity.	Ibuprofen	73-82	histocompatibility 2, class II antigen A, beta 1	Mus musculus	116-121