PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18325328-5 2008 However, the up-regulation of IL-10 as well as the down-regulation of TNF-alpha was abrogated when two tyrosine residues in the cytoplasmic tail of Siglec-9 were mutated to phenylalanine. Tyrosine 103-111 tumor necrosis factor Homo sapiens 70-79