PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18317936-2	2009	An oxysterol-induced interleukin-8 (IL-8) secretion in human monocytes/macrophages has been previously noticed, but the mechanisms remained unclear.	Oxysterols	3-12	C-X-C motif chemokine ligand 8	Homo sapiens	21-34	
18317936-2	2009	An oxysterol-induced interleukin-8 (IL-8) secretion in human monocytes/macrophages has been previously noticed, but the mechanisms remained unclear.	Oxysterols	3-12	C-X-C motif chemokine ligand 8	Homo sapiens	36-40	
18317936-3	2009	In this paper, we investigated the signaling pathways leading to the induction of IL-8 secretion in monocytic THP-1 cells treated with 7beta-hydroxycholesterol, a cytototoxic oxysterol, or with 25-hydroxycholesterol, an oxysterol non-cytotoxic toward this cell line.	Oxysterols	175-184	C-X-C motif chemokine ligand 8	Homo sapiens	82-86	
18317936-3	2009	In this paper, we investigated the signaling pathways leading to the induction of IL-8 secretion in monocytic THP-1 cells treated with 7beta-hydroxycholesterol, a cytototoxic oxysterol, or with 25-hydroxycholesterol, an oxysterol non-cytotoxic toward this cell line.	Oxysterols	220-229	C-X-C motif chemokine ligand 8	Homo sapiens	82-86	
18317936-4	2009	The oxysterol-induced IL-8 secretion appears to be a calcium-dependent phenomenon as shown by the use of calcium channel blockers, which strongly decreased IL-8 secretion and IL-8 messenger RNA (mRNA) levels.	Oxysterols	4-13	C-X-C motif chemokine ligand 8	Homo sapiens	22-26	
18317936-4	2009	The oxysterol-induced IL-8 secretion appears to be a calcium-dependent phenomenon as shown by the use of calcium channel blockers, which strongly decreased IL-8 secretion and IL-8 messenger RNA (mRNA) levels.	Oxysterols	4-13	C-X-C motif chemokine ligand 8	Homo sapiens	156-160	
18317936-4	2009	The oxysterol-induced IL-8 secretion appears to be a calcium-dependent phenomenon as shown by the use of calcium channel blockers, which strongly decreased IL-8 secretion and IL-8 messenger RNA (mRNA) levels.	Oxysterols	4-13	C-X-C motif chemokine ligand 8	Homo sapiens	156-160	
18317936-8	2009	These results demonstrate that oxysterol-induced IL-8 secretion is a calcium-dependent phenomenon involving the MEK/ERK1/2 pathway leading to the activation of IL-8 gene via AP-1 (c-fos).	Oxysterols	31-40	C-X-C motif chemokine ligand 8	Homo sapiens	49-53	
18317936-8	2009	These results demonstrate that oxysterol-induced IL-8 secretion is a calcium-dependent phenomenon involving the MEK/ERK1/2 pathway leading to the activation of IL-8 gene via AP-1 (c-fos).	Oxysterols	31-40	C-X-C motif chemokine ligand 8	Homo sapiens	160-164