PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18294632-0	2008	Chronic administration of morphine is associated with a decrease in surface AMPA GluR1 receptor subunit in dopamine D1 receptor expressing neurons in the shell and non-D1 receptor expressing neurons in the core of the rat nucleus accumbens.	Morphine	26-34	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	81-86	
18294632-3	2008	Immunogold electron microscopy was used to quantify the surface expression of the AMPA GluR1 subunit in dendritic profiles of neurons in the Acb in response to intermittent 14-day non-contingent injections of escalating doses of morphine, a model that parallels opioid self-administration.	Morphine	229-237	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	87-92	
18294632-6	2008	We provide the first report that chronic morphine administration is associated with a receptor-phenotypic decrease in surface trafficking of GluR1 in Acb subregions.	Morphine	41-49	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	141-146	
18294632-7	2008	When compared to saline injected animals, morphine produced a decrease in plasma membrane GluR1 labeling in medium- and large-sized D1R expressing dendritic profiles in the Acb shell.	Morphine	42-50	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	90-95	
18294632-9	2008	These results indicate that chronic intermittent injection of escalating doses of morphine is accompanied by ultrastructural plasticity of GluR1 in neurons that are responsive to glutamate and dopamine-induced D1R activation in the Acb shell, and neurons capable of responding to glutamate but not D1R receptor stimulation in the Acb core.	Morphine	82-90	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	139-144