PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18261462-2	2008	Based on transfection assays, phosphorylation of Runx1 at the three serine residues, Ser249, Ser266, and Ser276, was thought to be important for trans-activation activity of Runx1.	Serine	68-74	runt related transcription factor 1	Mus musculus	49-54	
18261462-2	2008	Based on transfection assays, phosphorylation of Runx1 at the three serine residues, Ser249, Ser266, and Ser276, was thought to be important for trans-activation activity of Runx1.	Serine	68-74	runt related transcription factor 1	Mus musculus	174-179	
18261462-3	2008	By using "knock-in" gene targeting, we generated mouse strains expressing mutant Runx1 protein that harbored a combined serine-to-alanine substitution at either of two residues, Ser249/Ser266 or Ser249/Ser276.	Serine	120-126	runt related transcription factor 1	Mus musculus	81-86	
18261462-6	2008	These results not only challenge the predicted regulation of Runx1 activity by phosphorylation at these serine residues, but also reaffirm the effectiveness of "knock-in" mutagenesis as a powerful tool for addressing the physiological relevance of post-translation modifications.	Serine	104-110	runt related transcription factor 1	Mus musculus	61-66