PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18063707-0	2008	Modulation of ileal bile acid transporter (ASBT) activity by depletion of plasma membrane cholesterol: association with lipid rafts.	Cholesterol	90-101	solute carrier family 10 member 2	Homo sapiens	43-47	
18063707-2	2008	To gain insight into the cellular regulation of ASBT, we investigated the association of ASBT with cholesterol and sphingolipid-enriched specialized plasma membrane microdomains known as lipid rafts and examined the role of membrane cholesterol in maintaining ASBT function.	Cholesterol	99-110	solute carrier family 10 member 2	Homo sapiens	89-93	
18063707-2	2008	To gain insight into the cellular regulation of ASBT, we investigated the association of ASBT with cholesterol and sphingolipid-enriched specialized plasma membrane microdomains known as lipid rafts and examined the role of membrane cholesterol in maintaining ASBT function.	Cholesterol	99-110	solute carrier family 10 member 2	Homo sapiens	89-93	
18063707-5	2008	Disruption of lipid rafts by depletion of membrane cholesterol with methyl-beta-cyclodextrin (MbetaCD) significantly reduced the association of ASBT with lipid rafts, which was paralleled by a decrease in ASBT activity in Caco-2 and HEK-293 cells treated with MbetaCD.	Cholesterol	51-62	solute carrier family 10 member 2	Homo sapiens	144-148	
18063707-8	2008	Our study illustrates that cholesterol content of lipid rafts is essential for the optimal activity of ASBT and support the association of ASBT with lipid rafts.	Cholesterol	27-38	solute carrier family 10 member 2	Homo sapiens	103-107	
18063707-8	2008	Our study illustrates that cholesterol content of lipid rafts is essential for the optimal activity of ASBT and support the association of ASBT with lipid rafts.	Cholesterol	27-38	solute carrier family 10 member 2	Homo sapiens	139-143	
18063707-9	2008	These findings suggest a novel mechanism by which ASBT activity may be rapidly modulated by alterations in cholesterol content of plasma membrane and thus have important implications in processes related to maintenance of bile acid and cholesterol homeostasis.	Cholesterol	107-118	solute carrier family 10 member 2	Homo sapiens	50-54	
18063707-9	2008	These findings suggest a novel mechanism by which ASBT activity may be rapidly modulated by alterations in cholesterol content of plasma membrane and thus have important implications in processes related to maintenance of bile acid and cholesterol homeostasis.	Cholesterol	236-247	solute carrier family 10 member 2	Homo sapiens	50-54