PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18025279-0 2007 Glycosaminoglycans and their synthetic mimetics inhibit RANTES-induced migration and invasion of human hepatoma cells. Glycosaminoglycans 0-18 C-C motif chemokine ligand 5 Homo sapiens 56-62 18025279-1 2007 The CC-chemokine regulated on activation, normal T-cell expressed, and presumably secreted (RANTES)/CCL5 mediates its biological activities through activation of G protein-coupled receptors, CCR1, CCR3, or CCR5, and binds to glycosaminoglycans. Glycosaminoglycans 225-243 C-C motif chemokine ligand 5 Homo sapiens 92-98 18025279-1 2007 The CC-chemokine regulated on activation, normal T-cell expressed, and presumably secreted (RANTES)/CCL5 mediates its biological activities through activation of G protein-coupled receptors, CCR1, CCR3, or CCR5, and binds to glycosaminoglycans. Glycosaminoglycans 225-243 C-C motif chemokine ligand 5 Homo sapiens 100-104 18025279-4 2007 RANTES/CCL5 binding to these cells depends on CCR1 and glycosaminoglycans. Glycosaminoglycans 55-73 C-C motif chemokine ligand 5 Homo sapiens 0-6 18025279-4 2007 RANTES/CCL5 binding to these cells depends on CCR1 and glycosaminoglycans. Glycosaminoglycans 55-73 C-C motif chemokine ligand 5 Homo sapiens 7-11 18025279-7 2007 The fact that RANTES/CCL5-induced migration and invasion of Huh7 cells are both strongly inhibited by anti-CCR1 antibodies and heparin, as well as by beta-d-xyloside treatment of the cells, suggests that CCR1 and glycosaminoglycans are involved in these events. Glycosaminoglycans 213-231 C-C motif chemokine ligand 5 Homo sapiens 14-20 18025279-7 2007 The fact that RANTES/CCL5-induced migration and invasion of Huh7 cells are both strongly inhibited by anti-CCR1 antibodies and heparin, as well as by beta-d-xyloside treatment of the cells, suggests that CCR1 and glycosaminoglycans are involved in these events. Glycosaminoglycans 213-231 C-C motif chemokine ligand 5 Homo sapiens 21-25 18025279-8 2007 We then show by surface plasmon resonance that synthetic glycosaminoglycan mimetics, OTR4120 or OTR4131, directly bind to RANTES/CCL5. Glycosaminoglycans 57-74 C-C motif chemokine ligand 5 Homo sapiens 122-128 18025279-8 2007 We then show by surface plasmon resonance that synthetic glycosaminoglycan mimetics, OTR4120 or OTR4131, directly bind to RANTES/CCL5. Glycosaminoglycans 57-74 C-C motif chemokine ligand 5 Homo sapiens 129-133 18025279-10 2007 Therefore, targeting the RANTES-glycosaminoglycan interaction could be a new therapeutic approach for human hepatocellular carcinoma. Glycosaminoglycans 32-49 C-C motif chemokine ligand 5 Homo sapiens 25-31