PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17720808-2 2007 In particular, reciprocal activation of phosphatidylinositol 3-kinases (PI3Ks) and small GTPases like Rac leads to accumulation, at the leading edge, of the PI3K product phosphatidylinositol 3,4,5-trisphosphate (PIP3). phosphatidylinositol 3,4,5-triphosphate 170-210 thymoma viral proto-oncogene 1 Mus musculus 102-105