PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17713901-2	2007	In the present paper, eight Molecular Dynamics (MD) simulations are carried out to examine the importance of structure and dynamics of water in the active site of both CDK2 and CDK5 complexes with roscovitine and indirubin analogues.	Roscovitine	197-208	cyclin dependent kinase 2	Homo sapiens	168-172	
17713901-5	2007	Different binding patterns of roscovitine in CDK2 and CDK5 are detected during the simulations because of the different binding conformations of the group on the C2 side chain, which might offer a clue toward finding highly selective inhibitors with regards to CDK2 and CDK5.	Roscovitine	30-41	cyclin dependent kinase 2	Homo sapiens	45-49	
17713901-5	2007	Different binding patterns of roscovitine in CDK2 and CDK5 are detected during the simulations because of the different binding conformations of the group on the C2 side chain, which might offer a clue toward finding highly selective inhibitors with regards to CDK2 and CDK5.	Roscovitine	30-41	cyclin dependent kinase 2	Homo sapiens	261-265