PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17686920-0 2007 Role of AHR2 in the expression of novel cytochrome P450 1 family genes, cell cycle genes, and morphological defects in developing zebra fish exposed to 3,3",4,4",5-pentachlorobiphenyl or 2,3,7,8-tetrachlorodibenzo-p-dioxin. 3,4,5,3',4'-pentachlorobiphenyl 152-183 aryl hydrocarbon receptor 2 Danio rerio 8-12 17686920-0 2007 Role of AHR2 in the expression of novel cytochrome P450 1 family genes, cell cycle genes, and morphological defects in developing zebra fish exposed to 3,3",4,4",5-pentachlorobiphenyl or 2,3,7,8-tetrachlorodibenzo-p-dioxin. 3,4,5,3',4'-pentachlorobiphenyl 152-183 peptidylprolyl isomerase Aa (cyclophilin A) Danio rerio 40-57 17686920-0 2007 Role of AHR2 in the expression of novel cytochrome P450 1 family genes, cell cycle genes, and morphological defects in developing zebra fish exposed to 3,3",4,4",5-pentachlorobiphenyl or 2,3,7,8-tetrachlorodibenzo-p-dioxin. Polychlorinated Dibenzodioxins 187-222 aryl hydrocarbon receptor 2 Danio rerio 8-12 17686920-4 2007 Basal and PCB126-induced expression of CYP1A, CYP1B1, CYP1C1, and CYP1C2 was examined over time as well as in relation to cell cycle gene expression and morphological effects of PCB126 in developing zebra fish. 3,4,5,3',4'-pentachlorobiphenyl 10-16 cytochrome P450, family 1, subfamily A Danio rerio 39-44 17686920-4 2007 Basal and PCB126-induced expression of CYP1A, CYP1B1, CYP1C1, and CYP1C2 was examined over time as well as in relation to cell cycle gene expression and morphological effects of PCB126 in developing zebra fish. 3,4,5,3',4'-pentachlorobiphenyl 10-16 cytochrome P450, family 1, subfamily B, polypeptide 1 Danio rerio 46-52 17686920-4 2007 Basal and PCB126-induced expression of CYP1A, CYP1B1, CYP1C1, and CYP1C2 was examined over time as well as in relation to cell cycle gene expression and morphological effects of PCB126 in developing zebra fish. 3,4,5,3',4'-pentachlorobiphenyl 10-16 cytochrome P450, family 1, subfamily C, polypeptide 1 Danio rerio 54-60 17686920-4 2007 Basal and PCB126-induced expression of CYP1A, CYP1B1, CYP1C1, and CYP1C2 was examined over time as well as in relation to cell cycle gene expression and morphological effects of PCB126 in developing zebra fish. 3,4,5,3',4'-pentachlorobiphenyl 10-16 cytochrome P450, family 1, subfamily C, polypeptide 2 Danio rerio 66-72 17686920-7 2007 PCB126 (0.3-100nM) caused concentration-dependent CYP1 gene induction (EC50: 1.4-2.7nM, Lowest observed effect concentration [LOEC]: 0.3-1nM) and pericardial edema (EC50: 4.4nM, LOEC: 3nM) in 3-dpf embryos. 3,4,5,3',4'-pentachlorobiphenyl 0-6 peptidylprolyl isomerase Aa (cyclophilin A) Danio rerio 50-54 17686920-8 2007 Blockage of AHR2 translation significantly inhibited these effects of PCB126 and TCDD. 3,4,5,3',4'-pentachlorobiphenyl 70-76 aryl hydrocarbon receptor 2 Danio rerio 12-16 17686920-8 2007 Blockage of AHR2 translation significantly inhibited these effects of PCB126 and TCDD. Polychlorinated Dibenzodioxins 81-85 aryl hydrocarbon receptor 2 Danio rerio 12-16 17686920-9 2007 PCNA gene expression was reduced by PCB126 in a concentration-dependent manner, suggesting that PCB126 could suppress cell proliferation. 3,4,5,3',4'-pentachlorobiphenyl 36-42 proliferating cell nuclear antigen Danio rerio 0-4 17686920-9 2007 PCNA gene expression was reduced by PCB126 in a concentration-dependent manner, suggesting that PCB126 could suppress cell proliferation. 3,4,5,3',4'-pentachlorobiphenyl 96-102 proliferating cell nuclear antigen Danio rerio 0-4 17686920-10 2007 Our results indicate that the four CYP1 genes examined are regulated by AHR2 and that the effect of PCB126 on morphology in zebra fish embryos is AHR2 dependent. 3,4,5,3',4'-pentachlorobiphenyl 100-106 peptidylprolyl isomerase Aa (cyclophilin A) Danio rerio 35-39 17686920-10 2007 Our results indicate that the four CYP1 genes examined are regulated by AHR2 and that the effect of PCB126 on morphology in zebra fish embryos is AHR2 dependent. 3,4,5,3',4'-pentachlorobiphenyl 100-106 aryl hydrocarbon receptor 2 Danio rerio 146-150 17686920-11 2007 Moreover, the developmental patterns of expression and induction suggest that CYP1 enzymes could function in normal development and in developmental toxicity of PCB126 in fish embryos. 3,4,5,3',4'-pentachlorobiphenyl 161-167 peptidylprolyl isomerase Aa (cyclophilin A) Danio rerio 78-82