PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17634555-0	2007	Doxorubicin directs the accumulation of interleukin-12 induced IFN gamma into tumors for enhancing STAT1 dependent antitumor effect.	Doxorubicin	0-11	interferon gamma	Mus musculus	63-72	
17634555-6	2007	To show that doxorubicin enhances the accumulation of IL-12-induced IFN gamma into tumors and the signal transducer and activator of transcription 1 (Stat1)-dependent antitumor efficacy, the distribution of IFN gamma and the therapeutic end points, such as T-cell infiltration, inhibition of tumor vessel density, tumor growth inhibition, and inhibition of spontaneous tumor metastasis in wild-type and Stat1(-/-) host and tumors were determined after the treatment at the indicated time points.	Doxorubicin	13-24	interferon gamma	Mus musculus	68-77	
17634555-6	2007	To show that doxorubicin enhances the accumulation of IL-12-induced IFN gamma into tumors and the signal transducer and activator of transcription 1 (Stat1)-dependent antitumor efficacy, the distribution of IFN gamma and the therapeutic end points, such as T-cell infiltration, inhibition of tumor vessel density, tumor growth inhibition, and inhibition of spontaneous tumor metastasis in wild-type and Stat1(-/-) host and tumors were determined after the treatment at the indicated time points.	Doxorubicin	13-24	interferon gamma	Mus musculus	207-216	
17634555-8	2007	We discovered that doxorubicin enhances the accumulation of IL-12-induced IFN gamma in tumors.	Doxorubicin	19-30	interferon gamma	Mus musculus	74-83	
17634555-9	2007	The doxorubicin-mediated accumulation of IFN gamma in tumors is caused by an increased accumulation of IFN gamma-secreting immune cells and not by a direct translocation of IFN gamma protein into tumors.	Doxorubicin	4-15	interferon gamma	Mus musculus	41-50	
17634555-9	2007	The doxorubicin-mediated accumulation of IFN gamma in tumors is caused by an increased accumulation of IFN gamma-secreting immune cells and not by a direct translocation of IFN gamma protein into tumors.	Doxorubicin	4-15	interferon gamma	Mus musculus	103-112	
17634555-9	2007	The doxorubicin-mediated accumulation of IFN gamma in tumors is caused by an increased accumulation of IFN gamma-secreting immune cells and not by a direct translocation of IFN gamma protein into tumors.	Doxorubicin	4-15	interferon gamma	Mus musculus	103-112	
17634555-10	2007	Depletion of immune cells reverses the doxorubicin-mediated accumulation of IFN gamma into tumors and reverses the inhibition of tumor vessel density induced by coadministration of doxorubicin and IL-12 DNA.	Doxorubicin	39-50	interferon gamma	Mus musculus	76-85	
17634555-11	2007	Knocking out IFN gamma signaling in the tumor host reverses the significant inhibition of tumor growth by coadministration of doxorubicin and IL-12.	Doxorubicin	126-137	interferon gamma	Mus musculus	13-22	
17634555-12	2007	CONCLUSIONS: The enhanced antitumor efficacy by coadministration of doxorubicin and IL-12 is dependent on the accumulation of IFN gamma in tumors.	Doxorubicin	68-79	interferon gamma	Mus musculus	126-135