PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17533422-4 2007 KEY RESULTS: Native ligands stimulated Gs and Gi activation through CRF(1), resulting in stimulation and then inhibition of cAMP accumulation. Cyclic AMP 124-128 corticotropin releasing hormone receptor 1 Homo sapiens 68-73 17533422-5 2007 Single replacements in urocortin at positions 6-15 led, dependent on the position and nature of the substituent, to ligands that conserved Gs activity, but were devoid of Gi activity, only stimulating cAMP accumulation, and competitively antagonized the Gi activation by sauvagine. Cyclic AMP 201-205 urocortin Homo sapiens 23-32