PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17504983-2	2007	It is attempted to know how Hsp27 endues cell with cisplatin resistance by interfering with upstream of both apoptosis signal-regulating kinase 1 (ASK1)/p38 mitogen-activated protein kinase-activated apoptotic signaling and serine/threonine kinase Akt-dependent survival signaling.	Cisplatin	51-60	mitogen-activated protein kinase 14	Homo sapiens	153-156	
17504983-4	2007	The cisplatin-induced apoptosis and activation of ASK1, p38, and Akt were compared in control cells, cells overexpressing Hsp27, and cells with their endogenous Hsp27 knocked down.	Cisplatin	4-13	mitogen-activated protein kinase 14	Homo sapiens	56-59	
17504983-6	2007	The p38 inhibitors obviously decreased whereas Akt inhibitors markedly increased the apoptotic fraction in cisplatin-treated cells.	Cisplatin	107-116	mitogen-activated protein kinase 14	Homo sapiens	4-7	
17504983-10	2007	CONCLUSIONS: Hsp27 endues cells with cisplatin resistance via depression of the drug-induced ASK1/p38 activation and enhancement of the drug-induced Akt activation.	Cisplatin	37-46	mitogen-activated protein kinase 14	Homo sapiens	98-101