PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17494760-0 2007 Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation. Tyrosine 98-106 tyrosine kinase non receptor 2 Homo sapiens 34-38 17494760-7 2007 Ack1 knockdown inhibited heregulin-dependent AR tyrosine phosphorylation, AR reporter activity, androgen-stimulated gene expression, and AR recruitment. Tyrosine 48-56 tyrosine kinase non receptor 2 Homo sapiens 0-4 17494760-9 2007 In 8 of 18 primary androgen-independent prostate tumor samples, tyrosine-phosphorylated AR protein was detected and correlated with the detection of tyrosine-phosphorylated Ack1. Tyrosine 64-72 tyrosine kinase non receptor 2 Homo sapiens 173-177 17494760-9 2007 In 8 of 18 primary androgen-independent prostate tumor samples, tyrosine-phosphorylated AR protein was detected and correlated with the detection of tyrosine-phosphorylated Ack1. Tyrosine 149-157 tyrosine kinase non receptor 2 Homo sapiens 173-177 17494760-11 2007 Activated Ack1 phosphorylated AR protein at Tyr-267 and Tyr-363, both located within the transactivation domain. Tyrosine 44-47 tyrosine kinase non receptor 2 Homo sapiens 10-14 17494760-11 2007 Activated Ack1 phosphorylated AR protein at Tyr-267 and Tyr-363, both located within the transactivation domain. Tyrosine 56-59 tyrosine kinase non receptor 2 Homo sapiens 10-14 17494760-12 2007 Mutation of Tyr-267 completely abrogated and mutation of Tyr-363 reduced Ack1-induced AR reporter activation and recruitment of AR to the androgen-responsive enhancer. Tyrosine 12-15 tyrosine kinase non receptor 2 Homo sapiens 73-77 17494760-12 2007 Mutation of Tyr-267 completely abrogated and mutation of Tyr-363 reduced Ack1-induced AR reporter activation and recruitment of AR to the androgen-responsive enhancer. Tyrosine 57-60 tyrosine kinase non receptor 2 Homo sapiens 73-77