PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17460390-0 2007 Angiotensin II-induced regulation of the expression and localization of iron metabolism-related genes in the rat kidney. Iron 72-76 angiotensinogen Rattus norvegicus 0-14 17460390-2 2007 We have previously shown that the administration of angiotensin II alters iron homeostasis in the rat kidney, which may in turn aggravate angiotensin II-induced renal damage. Iron 74-78 angiotensinogen Rattus norvegicus 52-66 17460390-2 2007 We have previously shown that the administration of angiotensin II alters iron homeostasis in the rat kidney, which may in turn aggravate angiotensin II-induced renal damage. Iron 74-78 angiotensinogen Rattus norvegicus 138-152 17460390-6 2007 Staining of serial sections revealed that some, but not all, of the renal tubular cells positive for these genes contained iron deposits in the kidney of angiotensin II-infused animals. Iron 123-127 angiotensinogen Rattus norvegicus 154-168 17460390-7 2007 Real-time polymerase chain reaction (PCR) showed that the mRNA expression of TfR, iron-responsive element-negative DMT1, FPN, and hepcidin mRNA increased ~1.9-fold, ~1.7-fold, ~2.3-fold, and ~4.7-fold, respectively, after angiotensin II infusion as compared with that of untreated controls, and that these increases could be suppressed by the concomitant administration of losartan. Iron 82-86 angiotensinogen Rattus norvegicus 222-236