PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1740713-3 1992 A muscarinic receptor radioligand, carbon-11-(+)-2 alpha-tropanyl benzilate ([11C]TRB), has been prepared through N-[11C]methylation of N-desmethyl TRB, and evaluated in rodents and primates. carbon-11-(+)-2 alpha-tropanyl benzilate 35-75 T cell receptor beta locus Homo sapiens 82-85 1740713-3 1992 A muscarinic receptor radioligand, carbon-11-(+)-2 alpha-tropanyl benzilate ([11C]TRB), has been prepared through N-[11C]methylation of N-desmethyl TRB, and evaluated in rodents and primates. carbon-11-(+)-2 alpha-tropanyl benzilate 35-75 T cell receptor beta locus Homo sapiens 148-151 1740713-3 1992 A muscarinic receptor radioligand, carbon-11-(+)-2 alpha-tropanyl benzilate ([11C]TRB), has been prepared through N-[11C]methylation of N-desmethyl TRB, and evaluated in rodents and primates. Carbon-11 78-81 T cell receptor beta locus Homo sapiens 82-85 1740713-3 1992 A muscarinic receptor radioligand, carbon-11-(+)-2 alpha-tropanyl benzilate ([11C]TRB), has been prepared through N-[11C]methylation of N-desmethyl TRB, and evaluated in rodents and primates. Carbon-11 78-81 T cell receptor beta locus Homo sapiens 148-151 1740713-5 1992 Comparisons with [11C]scopolamine in rats showed 2-6 times greater brain uptake of [11C] TRB. Carbon-11 18-21 T cell receptor beta locus Homo sapiens 89-92 1740713-5 1992 Comparisons with [11C]scopolamine in rats showed 2-6 times greater brain uptake of [11C] TRB. Scopolamine 22-33 T cell receptor beta locus Homo sapiens 89-92 1740713-6 1992 Highly specific and saturable binding of [11C]TRB in the striatum and cortex was demonstrated by greater than 85% blockade of uptake following QNB or scopolamine pretreatment. Quinuclidinyl Benzilate 143-146 T cell receptor beta locus Homo sapiens 46-49 1740713-6 1992 Highly specific and saturable binding of [11C]TRB in the striatum and cortex was demonstrated by greater than 85% blockade of uptake following QNB or scopolamine pretreatment. Scopolamine 150-161 T cell receptor beta locus Homo sapiens 46-49 1740713-8 1992 TLC analysis of rat tissues showed the absence of 11C-metabolites in brain and heart, and a rapid solid phase C-18 Sep-Pak method found that unmetabolized plasma [11C]TRB in monkeys fell from 81% at 5 min to 48% at 80 min. Carbon-11 163-166 T cell receptor beta locus Homo sapiens 167-170