PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17394422-6 2007 In intact mitochondria, the extent and duration of SOD1 activation was inversely correlated with mitochondrial superoxide production. Superoxides 111-121 superoxide dismutase 1 Rattus norvegicus 51-55 17394422-10 2007 Activation of IMS SOD1 by exogenous H2O2 delayed CaCl2-induced loss of transmembrane potential, decreased cytochrome c release and markedly prevented superoxide-induced loss of aconitase activity in intact mitochondria respiring at state-3. Superoxides 150-160 superoxide dismutase 1 Rattus norvegicus 18-22 17394422-11 2007 These findings suggest that H2O2, superoxide and TxrR-1 regulate IMS SOD1 activity reversibly, and that the active enzyme is implicated in protecting vital mitochondrial functions. Superoxides 34-44 superoxide dismutase 1 Rattus norvegicus 69-73