PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17387141-0	2007	Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalpha kinase activation.	fisetin	0-7	cyclin dependent kinase 6	Homo sapiens	25-50	
17387141-0	2007	Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalpha kinase activation.	fisetin	0-7	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	189-250	
17387141-5	2007	We found that among nine different flavones tested, fisetin was potent in suppressing tumor necrosis factor (TNF)-induced NF-kappaB activation.	Flavones	35-43	tumor necrosis factor	Homo sapiens	86-107	
17387141-5	2007	We found that among nine different flavones tested, fisetin was potent in suppressing tumor necrosis factor (TNF)-induced NF-kappaB activation.	Flavones	35-43	tumor necrosis factor	Homo sapiens	109-112	
17387141-5	2007	We found that among nine different flavones tested, fisetin was potent in suppressing tumor necrosis factor (TNF)-induced NF-kappaB activation.	fisetin	52-59	tumor necrosis factor	Homo sapiens	86-107	
17387141-5	2007	We found that among nine different flavones tested, fisetin was potent in suppressing tumor necrosis factor (TNF)-induced NF-kappaB activation.	fisetin	52-59	tumor necrosis factor	Homo sapiens	109-112	
17387141-6	2007	Fisetin also suppressed the NF-kappaB activation induced by various inflammatory agents and carcinogens, and it blocked the phosphorylation and degradation of IkappaBalpha by inhibiting IkappaBalpha (IKK) activation, which in turn led to suppression of the phosphorylation and nuclear translocation of p65.	fisetin	0-7	RELA proto-oncogene, NF-kB subunit	Homo sapiens	302-305	
17387141-8	2007	Fisetin also inhibited TNF-induced TAK1 and receptor-interacting protein activation, events that lie upstream of IKK activation.	fisetin	0-7	tumor necrosis factor	Homo sapiens	23-26	
17387141-8	2007	Fisetin also inhibited TNF-induced TAK1 and receptor-interacting protein activation, events that lie upstream of IKK activation.	fisetin	0-7	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	35-39