PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1738371-3 1992 The cyclic nucleotide analog 8-bromo-cAMP (cA) causes a greater than 50-fold increase in PA activity, the result of a 90% decrease in PAI-1 and a sustained 2-fold increase in tPA mRNA accumulation. 8-Bromo Cyclic Adenosine Monophosphate 29-41 serpin family E member 1 Rattus norvegicus 134-139