PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17379515-0 2007 Synthesis, characterization, and estrogen receptor binding affinity of flavone-, indole-, and furan-estradiol conjugates. flavone 71-78 estrogen receptor 1 Homo sapiens 33-50 17379515-3 2007 In vitro competitive binding assays for the estrogen receptor (alpha-ER), using [(3)H]estradiol (RBA=100) as a competitor, revealed that a two-carbon alkyl linker combined with a flavone conjugate provided the highest binding affinity (RBA approximately 9), warranting further studies on their potential use as selective estrogen-receptor modulators (SERMs) for hormone-replacement therapies. flavone 179-186 estrogen receptor 1 Homo sapiens 44-61