PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17360961-6 2007 EDN1 decreased (P </= 0.01) progesterone release and increased (P </= 0.01) PGF2alpha secretion and NOS activity via the PLC/PKC pathway in Day-9 CL, but not in Day-4 CL, cultured in vitro. Progesterone 31-43 endothelin-1 Oryctolagus cuniculus 0-4 17360961-6 2007 EDN1 decreased (P </= 0.01) progesterone release and increased (P </= 0.01) PGF2alpha secretion and NOS activity via the PLC/PKC pathway in Day-9 CL, but not in Day-4 CL, cultured in vitro. Dinoprost 82-91 endothelin-1 Oryctolagus cuniculus 0-4 17360961-7 2007 EDN1-induced, but not alfaprostol-induced luteolysis, was blocked by cotreatment in vivo with the ACE antagonist captopril. Captopril 113-122 endothelin-1 Oryctolagus cuniculus 0-4 17360961-7 2007 EDN1-induced, but not alfaprostol-induced luteolysis, was blocked by cotreatment in vivo with the ACE antagonist captopril. Captopril 113-122 angiotensin-converting enzyme Oryctolagus cuniculus 98-101 17360961-8 2007 These findings support the hypothesis that PGF2alpha regulates luteolysis through intraluteal activation of the renin-angiotensin/EDN1 systems in CL that have acquired luteolytic competence. Dinoprost 43-52 endothelin-1 Oryctolagus cuniculus 130-134