PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17336575-5 2007 In the present study, we present several lines of evidence to explain the role of over-expressed Ubc9 as a cofactor in the nuclear receptor and coactivator functions, including (i) activity that is independent of its ability to catalyze SUMO-1 conjugation, (ii) an insight into the protein-protein interaction motif in its eight C-terminal residues, (iii) selective coactivator function in nuclear receptor-relevant transactivation activities, and (iv) a non-trichostatin A-sensitive autonomous transcription repression domain in its far C-terminal region. trichostatin A 459-473 ubiquitin conjugating enzyme E2 I Homo sapiens 97-101