PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17272280-4 2007 Expression of p200 RhoGAP results in a significant increase of Ras-GTP and the activation of two downstream signaling pathways of Ras, ERK1/2 and phosphatidylinositol 3-kinase. ras-gtp 63-70 Rho GTPase activating protein 32 Homo sapiens 14-25 17272280-4 2007 Expression of p200 RhoGAP results in a significant increase of Ras-GTP and the activation of two downstream signaling pathways of Ras, ERK1/2 and phosphatidylinositol 3-kinase. ras-gtp 63-70 mitogen-activated protein kinase 3 Homo sapiens 135-141 17272280-8 2007 Interestingly, the RhoGAP activity of the N-terminal RhoGAP domain in p200 RhoGAP is also required for its full transforming activity, and expression of a dominant negative RhoA mutant that blocks RhoA cycling between the GDP- and GTP-bound states suppresses p200 RhoGAP transformation. Guanosine Diphosphate 222-225 Rho GTPase activating protein 1 Homo sapiens 19-25 17272280-8 2007 Interestingly, the RhoGAP activity of the N-terminal RhoGAP domain in p200 RhoGAP is also required for its full transforming activity, and expression of a dominant negative RhoA mutant that blocks RhoA cycling between the GDP- and GTP-bound states suppresses p200 RhoGAP transformation. Guanosine Diphosphate 222-225 Rho GTPase activating protein 1 Homo sapiens 53-59 17272280-8 2007 Interestingly, the RhoGAP activity of the N-terminal RhoGAP domain in p200 RhoGAP is also required for its full transforming activity, and expression of a dominant negative RhoA mutant that blocks RhoA cycling between the GDP- and GTP-bound states suppresses p200 RhoGAP transformation. Guanosine Diphosphate 222-225 Rho GTPase activating protein 32 Homo sapiens 70-81 17272280-8 2007 Interestingly, the RhoGAP activity of the N-terminal RhoGAP domain in p200 RhoGAP is also required for its full transforming activity, and expression of a dominant negative RhoA mutant that blocks RhoA cycling between the GDP- and GTP-bound states suppresses p200 RhoGAP transformation. Guanosine Diphosphate 222-225 ras homolog family member A Homo sapiens 173-177 17272280-8 2007 Interestingly, the RhoGAP activity of the N-terminal RhoGAP domain in p200 RhoGAP is also required for its full transforming activity, and expression of a dominant negative RhoA mutant that blocks RhoA cycling between the GDP- and GTP-bound states suppresses p200 RhoGAP transformation. Guanosine Diphosphate 222-225 ras homolog family member A Homo sapiens 197-201 17272280-8 2007 Interestingly, the RhoGAP activity of the N-terminal RhoGAP domain in p200 RhoGAP is also required for its full transforming activity, and expression of a dominant negative RhoA mutant that blocks RhoA cycling between the GDP- and GTP-bound states suppresses p200 RhoGAP transformation. Guanosine Triphosphate 231-234 Rho GTPase activating protein 1 Homo sapiens 19-25 17272280-8 2007 Interestingly, the RhoGAP activity of the N-terminal RhoGAP domain in p200 RhoGAP is also required for its full transforming activity, and expression of a dominant negative RhoA mutant that blocks RhoA cycling between the GDP- and GTP-bound states suppresses p200 RhoGAP transformation. Guanosine Triphosphate 231-234 Rho GTPase activating protein 1 Homo sapiens 53-59 17272280-8 2007 Interestingly, the RhoGAP activity of the N-terminal RhoGAP domain in p200 RhoGAP is also required for its full transforming activity, and expression of a dominant negative RhoA mutant that blocks RhoA cycling between the GDP- and GTP-bound states suppresses p200 RhoGAP transformation. Guanosine Triphosphate 231-234 Rho GTPase activating protein 32 Homo sapiens 70-81 17272280-8 2007 Interestingly, the RhoGAP activity of the N-terminal RhoGAP domain in p200 RhoGAP is also required for its full transforming activity, and expression of a dominant negative RhoA mutant that blocks RhoA cycling between the GDP- and GTP-bound states suppresses p200 RhoGAP transformation. Guanosine Triphosphate 231-234 ras homolog family member A Homo sapiens 173-177 17272280-8 2007 Interestingly, the RhoGAP activity of the N-terminal RhoGAP domain in p200 RhoGAP is also required for its full transforming activity, and expression of a dominant negative RhoA mutant that blocks RhoA cycling between the GDP- and GTP-bound states suppresses p200 RhoGAP transformation. Guanosine Triphosphate 231-234 ras homolog family member A Homo sapiens 197-201