PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17268847-3	2007	Treatment of H19-7 cells with bFGF increased NO production through upregulated iNOS/ nNOS expression, and also increased expressions of neuronal markers such as brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT3) and Neuro-D. Pretreatment of the cells with nicotine decreased iNOS promoter activity as well as iNOS/nNOS expression induced by bFGF, resulting in decreased NO production.	Nicotine	268-276	fibroblast growth factor 2	Rattus norvegicus	30-34	
17268847-0	2007	Nicotine inhibits bFGF-induced neurite outgrowth through suppression of NO synthesis in H19-7 cells.	Nicotine	0-8	fibroblast growth factor 2	Rattus norvegicus	18-22	
17268847-2	2007	In this study, we elucidated how nicotine inhibits neuronal differentiation induced by the basic fibroblast growth factor (bFGF) in hippocampal cell line, H19-7 cells, because nicotine is one of the key neuroregulatory components.	Nicotine	33-41	fibroblast growth factor 2	Rattus norvegicus	91-121	
17268847-2	2007	In this study, we elucidated how nicotine inhibits neuronal differentiation induced by the basic fibroblast growth factor (bFGF) in hippocampal cell line, H19-7 cells, because nicotine is one of the key neuroregulatory components.	Nicotine	33-41	fibroblast growth factor 2	Rattus norvegicus	123-127	
17268847-2	2007	In this study, we elucidated how nicotine inhibits neuronal differentiation induced by the basic fibroblast growth factor (bFGF) in hippocampal cell line, H19-7 cells, because nicotine is one of the key neuroregulatory components.	Nicotine	176-184	fibroblast growth factor 2	Rattus norvegicus	91-121	
17268847-2	2007	In this study, we elucidated how nicotine inhibits neuronal differentiation induced by the basic fibroblast growth factor (bFGF) in hippocampal cell line, H19-7 cells, because nicotine is one of the key neuroregulatory components.	Nicotine	176-184	fibroblast growth factor 2	Rattus norvegicus	123-127	
17268847-4	2007	Nicotine also suppressed expressions of BDNF, NT3 and Neuro-D, resulting in decreased bFGF-induced neurite outgrowth.	Nicotine	0-8	fibroblast growth factor 2	Rattus norvegicus	86-90	
17268847-5	2007	These results indicate that nicotine inhibits bFGF-induced neuronal differentiation in H19-7 cells through inhibition of NO formation by suppressing iNOS/nNOS expressions.	Nicotine	28-36	fibroblast growth factor 2	Rattus norvegicus	46-50